HitPredict

Interactor 1: YBOX1 (P67809)
Y-box-binding protein 1 (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Nuclease-sensitive element-binding protein 1) (Y-box transcription factor)
Gene: YBX1

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	24981860, 23986595
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CSD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 324 Hs			1 644
+	Hs
		516455 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		1031465 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		931406 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Hs
		516350 YBOX3_HUMAN (46-324): 2.21e-55: 186: 51.69		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Mm
		1225251 LN28A_MOUSE (30-186): 1.07e-40: 143: 24.39		Q99LF8_MOUSE (1-644): 0: 564: 95.30
+	Hs
		516697 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Mm
		665764 LN28A_MOUSE (30-186): 1.07e-40: 143: 24.39		PABP1_MOUSE (1-644): 0: 542: 74.69
+	Hs
		474013 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		474028 LN28B_HUMAN (33-275): 3.38e-55: 182: 24.41		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		582215 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		474045 YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		1055882 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15
+	Hs
		931325 YBOX1_HUMAN (1-324): 4.21e-69: 220: 100.00		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		474037 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		563174 YBOX3_HUMAN (46-324): 2.21e-55: 186: 51.69		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		1288651 YBOX2_HUMAN (23-314): 7.22e-48: 166: 44.15		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		582501 LN28A_HUMAN (50-217): 1.06e-42: 148: 23.46		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82