HitPredict

Interactor 1: CSK2B (P67870)
Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)
Gene: CSNK2B

Interactor 2: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.995

The method score is based on:

Property Details
Experiments 21777522, 26562092, 29997244, 9188720, 26264872, 24981860, 33961781, 11710515, 35271311, 12902976, 18560763, 10512750, 12901717, 11574463, 25852190, 23555304, 25519132, 10561590, 27705803, 30279146 and 19 others

more...
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, far western blotting, two hybrid, x-ray crystallography, pull down, enzymatic study, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping, validated two hybrid and 4 others

more...
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CK_II_beta~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005956 - protein kinase CK2 complex
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 215
Hs

1 391
+ Hs
+ Bt
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce
+ Dm
+ Sc
+ Sp
+ Dm
+ Sc
+ Sp
+ Sc
+ Dm
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024