HitPredict

Interactor 1: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 236
+	Hs
		418991 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		932019 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		418937 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		451303 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		931991 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		419027 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		925177 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Mm
		823530 CTRO_MOUSE (4-247): 3.96e-40: 148: 20.65		RAC1_MOUSE (32-217): 3.34e-76: 230: 53.23
+	Mm
		823539 CTRO_MOUSE (4-247): 3.96e-40: 148: 20.65		RHOA_MOUSE (33-215): 8.53e-73: 221: 42.62
+	Hs
		451225 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Rn
		92842 CTRO_RAT (4-247): 4.34e-39: 146: 20.24		RHOA_RAT (33-215): 8.53e-73: 221: 42.62
+	Mm
		823529 CTRO_MOUSE (4-247): 3.96e-40: 148: 20.65		CDC42_MOUSE (32-207): 2.12e-66: 205: 57.39