HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~FH2, Actin~WH2
Common GO terms	GO:0005884 - actin filament
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 1249
+	Hs
		891803 ACTB_HUMAN (4-377): 0: 599: 94.12		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		929884 ACTG_HUMAN (4-377): 0: 599: 94.39		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		892064 ACTB_HUMAN (4-377): 0: 599: 94.12		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		929974 ACTG_HUMAN (4-377): 0: 599: 94.39		FMNL2_HUMAN (10-1000): 6.58e-174: 545: 19.01
+	Hs
		892145 ACTB_HUMAN (4-377): 0: 599: 94.12		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		930071 ACTG_HUMAN (4-377): 0: 599: 94.39		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		892135 ACTB_HUMAN (4-377): 0: 599: 94.12		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		237575 ACTB_HUMAN (4-377): 0: 599: 94.12		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		237587 ACTC_HUMAN (1-377): 0: 599: 100.00		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		915429 ACTA_HUMAN (1-377): 0: 596: 98.41		FMNL3_HUMAN (43-382): 2.09e-59: 224: 20.68
+	Sp
		501585 ACT_SCHPO (4-377): 0: 645: 89.04		CDC12_SCHPO (1-270): 1.07e-20: 101: 15.96
+	Hs
		892076 ACTB_HUMAN (4-377): 0: 599: 94.12		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71
+	Hs
		930029 ACTG_HUMAN (4-377): 0: 599: 94.39		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71
+	Hs
		932414 ACTC_HUMAN (1-377): 0: 599: 100.00		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71