HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005925 - focal adhesion GO:0007015 - actin filament organization GO:0030017 - sarcomere GO:0030027 - lamellipodium
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 474
+	Hs
		892108 ACTB_HUMAN (4-377): 0: 599: 94.12		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		930051 ACTG_HUMAN (4-377): 0: 599: 94.39		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932355 ACTC_HUMAN (1-377): 0: 599: 100.00		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		932318 ACTC_HUMAN (1-377): 0: 599: 100.00		SNR40_HUMAN (160-435): 1.36e-38: 145: 11.87
+	Hs
		932185 ACTC_HUMAN (1-377): 0: 599: 100.00		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		891943 ACTB_HUMAN (4-377): 0: 599: 94.12		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		929956 ACTG_HUMAN (4-377): 0: 599: 94.39		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		884627 ACTB_HUMAN (4-377): 0: 599: 94.12		CORO7_HUMAN (2-203): 2.45e-23: 105: 12.22
+	Hs
		891660 ACTB_HUMAN (4-377): 0: 599: 94.12		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		903110 ACTG_HUMAN (4-377): 0: 599: 94.39		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39