HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 721
+	Hs
		892144 ACTB_HUMAN (4-377): 0: 599: 94.12		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		930070 ACTG_HUMAN (4-377): 0: 599: 94.39		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		891807 ACTB_HUMAN (4-377): 0: 599: 94.12		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		929885 ACTG_HUMAN (4-377): 0: 599: 94.39		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		932190 ACTC_HUMAN (1-377): 0: 599: 100.00		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Mm
		892205 ACTB_MOUSE (4-377): 0: 599: 94.12		MYH9_MOUSE (218-628): 1.68e-13: 76.8: 9.44
+	Hs
		929935 ACTG_HUMAN (4-377): 0: 599: 94.39		DLG5_HUMAN (219-569): 1.09e-12: 74.1: 10.72
+	Hs
		891935 ACTB_HUMAN (4-377): 0: 599: 94.12		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		929952 ACTG_HUMAN (4-377): 0: 599: 94.39		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		932297 ACTC_HUMAN (1-377): 0: 599: 100.00		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		933030 ACTS_HUMAN (1-377): 0: 599: 98.94		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		725136 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Rn
		892236 ACTB_RAT (4-377): 0: 599: 94.12		MYH10_RAT (466-719): 7.5e-11: 67.9: 16.93
+	Rn
		892228 ACTB_RAT (4-377): 0: 599: 94.12		MYH9_RAT (331-715): 1.22e-10: 67.2: 13.51
+	Hs
		724738 ACTB_HUMAN (4-377): 0: 599: 94.12		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		724762 ACTG_HUMAN (4-377): 0: 599: 94.39		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		724766 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		724767 ACTS_HUMAN (1-377): 0: 599: 98.94		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		725135 ACTH_HUMAN (4-377): 0: 591: 98.93		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93