HitPredict

Interactor 1: UB2L3 (P68036)
Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)
Gene: UBE2L3

Interactor 2: ZN598 (Q86UK7)
E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598)
Gene: ZNF598

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28685749, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 154 Hs			1 904
+	Hs
		849354 UB2D1_HUMAN (2-149): 5.66e-75: 221: 38.26		ZN598_HUMAN (1-904): 3.02e-165: 506: 100.00
+	Hs
		919768 UB2D2_HUMAN (2-149): 7.95e-75: 221: 37.58		ZN598_HUMAN (1-904): 3.02e-165: 506: 100.00
+	Hs
		895833 UB2D3_HUMAN (2-149): 8.29e-74: 218: 36.91		ZN598_HUMAN (1-904): 3.02e-165: 506: 100.00
+	Sc
		549835 UBC4_YEAST (1-148): 8.58e-75: 221: 40.27		HEL2_YEAST (29-271): 1.11e-97: 321: 28.63
+	Hs
		577603 UBE2A_HUMAN (3-150): 7.79e-65: 196: 26.17		SON_HUMAN (339-771): 7.47e-12: 72: 12.39