HitPredict

Interactor 1: E9PXB7 (E9PXB7)
E3 ubiquitin-protein ligase (EC 2.3.2.26)
Gene: Nedd4l

Interactor 2: 1433G (P61982)
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: Ywhag

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16613846
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Mm			1 247
+	Mm
		93264 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Mm
		910302 NED4L_MOUSE (1-835): 0: 951: 97.54		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		909930 NED4L_HUMAN (1-835): 0: 944: 95.79		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		905007 NED4L_HUMAN (1-835): 0: 944: 95.79		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982400 NED4L_HUMAN (1-835): 0: 944: 95.79		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Mm
		93281 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Mm
		1208289 NED4L_MOUSE (1-835): 0: 951: 97.54		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Mm
		93266 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433T_MOUSE (2-245): 3e-105: 306: 70.73
+	Hs
		683637 NED4L_HUMAN (1-835): 0: 944: 95.79		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927423 NED4L_HUMAN (1-835): 0: 944: 95.79		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647201 NED4L_HUMAN (1-835): 0: 944: 95.79		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		808077 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		93259 E9PXB7_MOUSE (1-835): 0: 959: 100.00		1433S_MOUSE (2-236): 1.38e-95: 281: 65.96
+	Hs
		808076 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		684276 NED4L_HUMAN (1-835): 0: 944: 95.79		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		808102 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		683192 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		808081 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646713 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683894 NEDD4_HUMAN (1-835): 0: 845: 60.41		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16