HitPredict

Interactor 1: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Interactor 2: EF1A2 (Q05639)
Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1)
Gene: EEF1A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

The method score is based on:

Property	Details
Experiments	33961781, 28514442, 35235311, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU_D3, GTP_EFTU_D2~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D3, GTP_EFTU_D3~GTP_EFTU_D3
Common GO terms	GO:0003746 - translation elongation factor activity GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005853 - eukaryotic translation elongation factor 1 complex and 5 others more... GO:0006412 - translation GO:0006414 - translational elongation GO:0019901 - protein kinase binding GO:0098574 - cytoplasmic side of lysosomal membrane GO:1904714 - regulation of chaperone-mediated autophagy
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	462
Hs

1	463

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024