HitPredict

Interactor 1: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Interactor 2: MK14 (Q16539)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
Gene: MAPK14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	31980649, 18624398, unassigned2173
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0034774 - secretory granule lumen and 1 others more... GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 360
+	Hs
		1082570 EF1A3_HUMAN (1-462): 0: 574: 99.57		MK14_HUMAN (1-360): 8.56e-158: 448: 100.00
+	Hs
		625342 EF1A1_HUMAN (1-462): 0: 578: 100.00		CDK2_HUMAN (21-316): 3.8e-148: 421: 36.76
+	Rn
		600366 EF1A1_RAT (1-462): 0: 577: 99.78		MK03_RAT (14-350): 2.59e-143: 412: 48.55
+	Hs
		173878 EF1A1_HUMAN (1-462): 0: 578: 100.00		MK13_HUMAN (4-360): 1.04e-142: 410: 59.78
+	Rn
		600367 EF1A2_RAT (1-461): 0: 566: 92.63		MK03_RAT (14-350): 2.59e-143: 412: 48.55
+	Hs
		960083 EF1A2_HUMAN (1-461): 0: 567: 92.63		CDK3_HUMAN (21-323): 3.15e-140: 401: 36.25
+	Sc
		367857 EF1A_YEAST (1-445): 0: 538: 80.90		HOG1_YEAST (3-349): 2.91e-143: 414: 51.15