HitPredict

Interactor 1: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006412 - translation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 334
+	Hs
		984411 EF1A2_HUMAN (1-461): 0: 567: 92.63		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		1272729 HBS1L_HUMAN (5-443): 5.78e-158: 464: 38.95		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		130843 EF1A1_HUMAN (1-462): 0: 578: 100.00		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		130859 EF1A2_HUMAN (1-461): 0: 567: 92.63		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		176996 EF1A1_HUMAN (1-462): 0: 578: 100.00		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57
+	Hs
		124827 EF1A1_HUMAN (1-462): 0: 578: 100.00		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Sc
		368172 EF1A_YEAST (1-445): 0: 538: 80.90		RPN11_YEAST (39-333): 9.57e-75: 234: 29.14
+	Sc
		368469 EF1A_YEAST (1-445): 0: 538: 80.90		RPN8_YEAST (53-326): 4.45e-57: 190: 16.61
+	Hs
		932743 EF1A1_HUMAN (1-462): 0: 578: 100.00		MYSM1_HUMAN (39-172): 3.5e-29: 119: 23.29
+	Hs
		176936 ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57
+	Hs
		124751 ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48