Interactor 1: FKB1B (P68106)
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
Gene: FKBP1B

Interactor 2: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FKBP_C~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010880 - regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 - regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0016020 - membrane
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 108
Hs

1 499
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024