Interactor 1: FKB1B (P68106)
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
Gene: FKBP1B

Interactor 2: RYR3 (Q15413)
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
Gene: RYR3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11598113
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FKBP_C~RYDR_ITPR, FKBP_C~SPRY
Common GO terms GO:0016020 - membrane
GO:0030018 - Z disc
GO:0033017 - sarcoplasmic reticulum membrane
GO:0034704 - calcium channel complex
GO:0051209 - release of sequestered calcium ion into cytosol
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 108
Hs

1 4870
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ Oc
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024