Interactor 1: FKB1B (P68106)
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
Gene: FKBP1B
Interactor 2: RYR3 (Q15413)
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
Gene: RYR3
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11598113 |
Identification Methods | pull down |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | FKBP_C~RYDR_ITPR, FKBP_C~SPRY |
Common GO terms | GO:0016020 - membrane GO:0030018 - Z disc GO:0033017 - sarcoplasmic reticulum membrane GO:0034704 - calcium channel complex GO:0051209 - release of sequestered calcium ion into cytosol |
Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024