HitPredict

Interactor 1: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Interactor 2: COTL1 (Q14019)
Coactosin-like protein
Gene: COTL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11297527
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0005829 - cytosol GO:0005884 - actin filament GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 142
+	Hs
		892099 ACTB_HUMAN (5-377): 0: 604: 93.83		DBNL_HUMAN (1-142): 1.29e-53: 176: 23.81
+	Hs
		932439 ACTC_HUMAN (1-377): 0: 604: 98.94		DBNL_HUMAN (1-142): 1.29e-53: 176: 23.81
+	Hs
		891757 ACTB_HUMAN (5-377): 0: 604: 93.83		COTL1_HUMAN (1-142): 8.17e-55: 170: 100.00
+	Hs
		929858 ACTG_HUMAN (4-377): 0: 604: 93.85		COTL1_HUMAN (1-142): 8.17e-55: 170: 100.00
+	Mm
		892211 ACTB_MOUSE (5-377): 0: 604: 93.83		COTL1_MOUSE (1-142): 1.12e-54: 169: 95.07
+	Mm
		929806 ACTG_MOUSE (4-377): 0: 604: 93.85		COTL1_MOUSE (1-142): 1.12e-54: 169: 95.07
+	Ce
		501469 ACT2_CAEEL (1-377): 0: 607: 94.16		Q9XUT0_CAEEL (1-142): 9.79e-45: 156: 21.38
+	Hs
		891799 ACTB_HUMAN (5-377): 0: 604: 93.83		DREB_HUMAN (1-132): 8.41e-44: 153: 17.78
+	Hs
		929879 ACTG_HUMAN (4-377): 0: 604: 93.85		DREB_HUMAN (1-132): 8.41e-44: 153: 17.78
+	Hs
		932187 ACTC_HUMAN (1-377): 0: 604: 98.94		DREB_HUMAN (1-132): 8.41e-44: 153: 17.78
+	Hs
		915391 ACTA_HUMAN (1-377): 0: 602: 97.88		DREB_HUMAN (1-132): 8.41e-44: 153: 17.78