HitPredict

Interactor 1: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12417592
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0030027 - lamellipodium GO:0030175 - filopodium GO:0048545 - response to steroid hormone
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 817
+	Hs
		891987 ACTB_HUMAN (5-377): 0: 604: 93.83		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Hs
		929975 ACTG_HUMAN (4-377): 0: 604: 93.85		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Hs
		915484 ACTA_HUMAN (1-377): 0: 602: 97.88		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Rn
		192522 ACTS_RAT (1-377): 0: 605: 100.00		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Rn
		192517 ACTB_RAT (5-377): 0: 604: 93.83		NEB2_RAT (1-817): 2.3e-118: 379: 95.23
+	Mm
		933086 ACTS_MOUSE (1-377): 0: 605: 100.00		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		892184 ACTB_MOUSE (5-377): 0: 604: 93.83		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		932490 ACTC_MOUSE (1-377): 0: 604: 98.94		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		892106 ACTB_HUMAN (5-377): 0: 604: 93.83		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Hs
		930050 ACTG_HUMAN (4-377): 0: 604: 93.85		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Mm
		929790 ACTG_MOUSE (4-377): 0: 604: 93.85		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		891759 ACTB_HUMAN (5-377): 0: 604: 93.83		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Mm
		892179 ACTB_MOUSE (5-377): 0: 604: 93.83		INADL_MOUSE (432-580): 5.24e-14: 78.7: 21.85