HitPredict

Interactor 1: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 548
+	Hs
		933032 ACTS_HUMAN (1-377): 0: 605: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		932311 ACTC_HUMAN (1-377): 0: 604: 98.94		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		933049 ACTS_HUMAN (1-377): 0: 605: 100.00		TRIM6_HUMAN (13-420): 1.73e-74: 246: 13.13
+	Hs
		584915 ACTB_HUMAN (5-377): 0: 604: 93.83		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		584922 ACTA_HUMAN (1-377): 0: 602: 97.88		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		930096 ACTH_HUMAN (4-377): 0: 597: 98.40		TRIM6_HUMAN (13-420): 1.73e-74: 246: 13.13
+	Hs
		932136 ACTC_HUMAN (1-377): 0: 604: 98.94		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		891904 ACTB_HUMAN (5-377): 0: 604: 93.83		TRI58_HUMAN (14-433): 2.08e-66: 225: 13.99
+	Hs
		891732 ACTB_HUMAN (5-377): 0: 604: 93.83		TRI26_HUMAN (12-339): 5.62e-65: 222: 16.23
+	Hs
		933048 ACTS_HUMAN (1-377): 0: 605: 100.00		TRI31_HUMAN (12-426): 1.42e-62: 213: 17.35
+	Hs
		892015 ACTB_HUMAN (5-377): 0: 604: 93.83		TRI31_HUMAN (12-426): 1.42e-62: 213: 17.35
+	Hs
		933006 ACTS_HUMAN (1-377): 0: 605: 100.00		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		891854 ACTB_HUMAN (5-377): 0: 604: 93.83		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		929906 ACTG_HUMAN (4-377): 0: 604: 93.85		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		932220 ACTC_HUMAN (1-377): 0: 604: 98.94		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		915417 ACTA_HUMAN (1-377): 0: 602: 97.88		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		892017 ACTB_HUMAN (5-377): 0: 604: 93.83		TRIM9_HUMAN (124-288): 9.61e-12: 69.7: 26.06
+	Hs
		932366 ACTC_HUMAN (1-377): 0: 604: 98.94		TRIM9_HUMAN (124-288): 9.61e-12: 69.7: 26.06
+	Hs
		930086 ACTH_HUMAN (4-377): 0: 597: 98.40		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		915499 ACTA_HUMAN (1-377): 0: 602: 97.88		TRIM9_HUMAN (124-288): 9.61e-12: 69.7: 26.06