HitPredict

Interactor 1: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Interactor 2: SCIN (Q9Y6U3)
Scinderin (Adseverin)
Gene: SCIN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12438125
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~Gelsolin
Common GO terms	GO:0015629 - actin cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 715
+	Hs
		892149 ACTB_HUMAN (5-377): 0: 604: 93.83		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		930076 ACTG_HUMAN (4-377): 0: 604: 93.85		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		932481 ACTC_HUMAN (1-377): 0: 604: 98.94		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		915546 ACTA_HUMAN (1-377): 0: 602: 97.88		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		413886 ACTS_HUMAN (1-377): 0: 605: 100.00		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413874 ACTB_HUMAN (5-377): 0: 604: 93.83		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413884 ACTG_HUMAN (4-377): 0: 604: 93.85		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413885 ACTC_HUMAN (1-377): 0: 604: 98.94		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		413881 ACTA_HUMAN (1-377): 0: 602: 97.88		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Oc
		101997 ACTB_RABIT (5-377): 0: 602: 93.57		G1U9R8_RABIT (2-715): 0: 1029: 59.86
+	Hs
		891735 ACTB_HUMAN (5-377): 0: 604: 93.83		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		929839 ACTG_HUMAN (4-377): 0: 604: 93.85		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		932132 ACTC_HUMAN (1-377): 0: 604: 98.94		FLII_HUMAN (6-713): 0: 741: 27.38
+	Dm
		950116 ACT6_DROME (1-377): 0: 600: 92.57		FLII_DROME (6-714): 0: 716: 27.89
+	Dm
		501491 ACT1_DROME (1-377): 0: 604: 93.63		QUAI_DROME (7-714): 0: 624: 23.26
+	Bt
		221227 ACTB_BOVIN (5-377): 0: 604: 93.83		SVIL_BOVIN (21-347): 2.8e-32: 137: 21.47
+	Hs
		313786 ACTB_HUMAN (5-377): 0: 604: 93.83		SVIL_HUMAN (21-347): 1.62e-31: 134: 21.73