HitPredict

Interactor 1: 1433T (P68254)
14-3-3 protein theta (14-3-3 protein tau)
Gene: Ywhaq

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 1161
+	Mm
		910338 1433E_MOUSE (2-243): 9.76e-145: 406: 63.93		TSC1_MOUSE (1-1161): 0: 771: 100.00
+	Hs
		909871 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Mm
		926881 1433Z_MOUSE (1-245): 1.97e-142: 400: 79.59		TSC1_MOUSE (1-1161): 0: 771: 100.00
+	Hs
		909755 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		PHLB1_HUMAN (281-916): 3.43e-37: 154: 14.88
+	Hs
		522602 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		MYH7_HUMAN (394-1133): 2.36e-26: 119: 8.63
+	Hs
		551660 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		724761 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		909658 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Mm
		926886 1433Z_MOUSE (1-245): 1.97e-142: 400: 79.59		MY18A_MOUSE (540-1147): 1.87e-24: 113: 10.97
+	Hs
		502907 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		MYH3_HUMAN (312-981): 2.28e-20: 100: 12.05
+	Zm
		5465 B6U284_MAIZE (1-243): 1.75e-143: 403: 60.32		A0A1D6DZK4_MAIZE (684-1161): 9.86e-17: 88.3: 9.21
+	Mm
		93548 1433E_MOUSE (2-243): 9.76e-145: 406: 63.93		DESP_MOUSE (706-1133): 3.64e-15: 83.3: 12.56
+	Mm
		926804 1433Z_MOUSE (1-245): 1.97e-142: 400: 79.59		MYH10_MOUSE (708-1000): 6.45e-15: 82.3: 14.77
+	Hs
		728460 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		MYH11_HUMAN (796-1161): 5.47e-11: 69.5: 12.30
+	Hs
		725130 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Mm
		926855 1433Z_MOUSE (1-245): 1.97e-142: 400: 79.59		MYH9_MOUSE (773-1161): 3.4e-11: 70.2: 11.72
+	Hs
		909488 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		CGNL1_HUMAN (722-989): 7.46e-09: 62.5: 21.07
+	Hs
		728466 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		MYH11_HUMAN (796-1161): 5.47e-11: 69.5: 12.30
+	Dm
		955019 1433E_DROME (2-242): 5.04e-143: 402: 65.43		Q9VCC9_DROME (779-1108): 3.26e-09: 63.3: 9.67
+	Mm
		926889 1433Z_MOUSE (1-245): 1.97e-142: 400: 79.59		PLEC_MOUSE (557-1006): 2.01e-09: 64.5: 13.40