HitPredict

Interactor 1: 1433T (P68255)
14-3-3 protein theta (14-3-3 protein tau)
Gene: Ywhaq

Interactor 2: NEDD4 (Q62940)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4)
Gene: NEDD4

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15677482
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019904 - protein domain specific binding GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Rn			1 887
+	Rn
		910358 1433E_RAT (2-243): 9.76e-145: 406: 63.93		NEDD4_RAT (1-887): 0: 927: 100.00
+	Mm
		808343 1433E_MOUSE (2-243): 9.76e-145: 406: 63.93		NEDD4_MOUSE (1-887): 0: 910: 94.59
+	Hs
		909930 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		NED4L_HUMAN (58-887): 0: 770: 56.21
+	Mm
		910302 1433E_MOUSE (2-243): 9.76e-145: 406: 63.93		NED4L_MOUSE (72-887): 0: 769: 57.23
+	Hs
		647201 1433T_HUMAN (1-245): 7.86e-142: 398: 99.59		NED4L_HUMAN (58-887): 0: 770: 56.21
+	Hs
		927423 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		NED4L_HUMAN (58-887): 0: 770: 56.21
+	Hs
		808077 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		NEDD4_HUMAN (154-887): 0: 724: 78.86
+	Hs
		646713 1433T_HUMAN (1-245): 7.86e-142: 398: 99.59		NEDD4_HUMAN (154-887): 0: 724: 78.86
+	Hs
		808081 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		NEDD4_HUMAN (154-887): 0: 724: 78.86
+	Hs
		647191 1433T_HUMAN (1-245): 7.86e-142: 398: 99.59		ITCH_HUMAN (62-884): 0: 686: 31.69
+	Hs
		125318 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		WWP2_HUMAN (72-884): 0: 677: 33.30
+	Hs
		125169 1433T_HUMAN (1-245): 7.86e-142: 398: 99.59		WWP2_HUMAN (72-884): 0: 677: 33.30
+	Hs
		125351 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		WWP2_HUMAN (72-884): 0: 677: 33.30
+	Mm
		93264 1433E_MOUSE (2-243): 9.76e-145: 406: 63.93		E9PXB7_MOUSE (169-887): 0: 651: 57.16
+	Hs
		647296 1433T_HUMAN (1-245): 7.86e-142: 398: 99.59		SMUF1_HUMAN (76-883): 0: 657: 33.21
+	Mm
		93266 1433T_MOUSE (1-245): 2.8e-141: 397: 100.00		E9PXB7_MOUSE (169-887): 0: 651: 57.16
+	Hs
		647267 1433T_HUMAN (1-245): 7.86e-142: 398: 99.59		WWP1_HUMAN (76-884): 0: 642: 31.52
+	Hs
		909745 1433E_HUMAN (2-243): 9.76e-145: 406: 63.93		HUWE1_HUMAN (158-885): 2.08e-167: 542: 27.96
+	Hs
		927228 1433Z_HUMAN (1-245): 1.19e-141: 398: 79.18		HUWE1_HUMAN (158-885): 2.08e-167: 542: 27.96
+	At
		788566 14333_ARATH (3-243): 6.02e-143: 401: 62.04		UPL2_ARATH (334-884): 1.61e-163: 531: 30.62