HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	28514442, 33961781, 35271311, 23190606
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005874 - microtubule GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 451 Hs			1 535
+	Hs
		1306647 TBA1C_HUMAN (1-451): 0: 728: 98.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Mm
		933713 TBA1A_MOUSE (1-440): 0: 715: 99.55		TCPH_MOUSE (4-534): 0: 599: 33.77
+	Hs
		943439 TBA1C_HUMAN (1-451): 0: 728: 98.00		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		933582 TBA4A_HUMAN (1-450): 0: 719: 96.44		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		933325 TBA1B_HUMAN (1-440): 0: 717: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1175131 TBA1A_HUMAN (1-440): 0: 715: 99.55		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		933404 TBA4A_HUMAN (1-450): 0: 719: 96.44		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		943313 TBA1A_HUMAN (1-440): 0: 715: 99.55		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		826850 TBA1C_HUMAN (1-451): 0: 728: 98.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826613 TBA4A_HUMAN (1-450): 0: 719: 96.44		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826612 TBA1B_HUMAN (1-440): 0: 717: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826733 TBA1A_HUMAN (1-440): 0: 715: 99.55		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		573448 TBA1C_HUMAN (1-451): 0: 728: 98.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821389 TBA1C_HUMAN (1-451): 0: 728: 98.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573214 TBA4A_HUMAN (1-450): 0: 719: 96.44		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821165 TBA4A_HUMAN (1-450): 0: 719: 96.44		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573213 TBA1B_HUMAN (1-440): 0: 717: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821164 TBA1B_HUMAN (1-440): 0: 717: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573332 TBA1A_HUMAN (1-440): 0: 715: 99.55		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821281 TBA1A_HUMAN (1-440): 0: 715: 99.55		TCPE_HUMAN (1-528): 0: 541: 32.29