HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: MP2K5 (Q13163)
Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)
Gene: MAP2K5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 451 Hs			1 448
+	Hs
		933422 TBA4A_HUMAN (1-450): 0: 719: 96.44		MP2K5_HUMAN (1-448): 4.77e-153: 443: 100.00
+	Hs
		160742 TBA1C_HUMAN (1-451): 0: 728: 98.00		AURKA_HUMAN (67-439): 1.27e-122: 364: 21.12
+	Hs
		681913 TBA1A_HUMAN (1-440): 0: 715: 99.55		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		428041 TBB5_HUMAN (1-439): 0: 699: 41.23		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		160334 TBB5_HUMAN (1-439): 0: 699: 41.23		AURKA_HUMAN (67-439): 1.27e-122: 364: 21.12
+	Hs
		1023101 TBA1C_HUMAN (1-451): 0: 728: 98.00		STK4_HUMAN (146-445): 8.05e-108: 329: 31.09
+	Hs
		1026217 TBA1C_HUMAN (1-451): 0: 728: 98.00		PAK1_HUMAN (94-420): 7.29e-104: 321: 28.11
+	Hs
		933421 TBA4A_HUMAN (1-450): 0: 719: 96.44		STK4_HUMAN (146-445): 8.05e-108: 329: 31.09
+	Ce
		110168 O18688_CAEEL (1-439): 0: 700: 87.70		GCK1_CAEEL (135-444): 7.62e-111: 342: 33.02
+	Hs
		933187 TBA1B_HUMAN (1-440): 0: 717: 100.00		PAK1_HUMAN (94-420): 7.29e-104: 321: 28.11
+	Hs
		1026181 TBA1A_HUMAN (1-440): 0: 715: 99.55		PAK1_HUMAN (94-420): 7.29e-104: 321: 28.11
+	Dm
		415650 TBA3_DROME (1-439): 0: 710: 97.04		DSOR1_DROME (115-446): 2.93e-106: 322: 37.12
+	Hs
		1026178 TBA3E_HUMAN (1-440): 0: 700: 96.59		PAK1_HUMAN (94-420): 7.29e-104: 321: 28.11
+	Hs
		735003 TBA1C_HUMAN (1-451): 0: 728: 98.00		MP2K2_HUMAN (146-448): 4.5e-81: 257: 40.06
+	Hs
		734911 TBA4A_HUMAN (1-450): 0: 719: 96.44		MP2K2_HUMAN (146-448): 4.5e-81: 257: 40.06
+	Hs
		734910 TBA1B_HUMAN (1-440): 0: 717: 100.00		MP2K2_HUMAN (146-448): 4.5e-81: 257: 40.06
+	Hs
		734964 TBA1A_HUMAN (1-440): 0: 715: 99.55		MP2K2_HUMAN (146-448): 4.5e-81: 257: 40.06
+	Hs
		428055 TBB5_HUMAN (1-439): 0: 699: 41.23		MP2K2_HUMAN (146-448): 4.5e-81: 257: 40.06
+	Hs
		805463 TBA1C_HUMAN (1-451): 0: 728: 98.00		MP2K3_HUMAN (158-418): 1.56e-66: 218: 45.09
+	Hs
		805386 TBA1B_HUMAN (1-440): 0: 717: 100.00		MP2K3_HUMAN (158-418): 1.56e-66: 218: 45.09