HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12481031
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 451 Hs			1 759
+	Hs
		1043193 TBA1C_HUMAN (1-451): 0: 728: 98.00		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		933435 TBA4A_HUMAN (1-450): 0: 719: 96.44		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		428194 TBB5_HUMAN (1-439): 0: 699: 41.23		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043545 TBA1C_HUMAN (1-451): 0: 728: 98.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		933436 TBA4A_HUMAN (1-450): 0: 719: 96.44		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		933200 TBA1B_HUMAN (1-440): 0: 717: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1042396 TBA1C_HUMAN (1-451): 0: 728: 98.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		933434 TBA4A_HUMAN (1-450): 0: 719: 96.44		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		933198 TBA1B_HUMAN (1-440): 0: 717: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041883 TBA1A_HUMAN (1-440): 0: 715: 99.55		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		428193 TBB5_HUMAN (1-439): 0: 699: 41.23		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041174 TBA1C_HUMAN (1-451): 0: 728: 98.00		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		933432 TBA4A_HUMAN (1-450): 0: 719: 96.44		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1041061 TBA1A_HUMAN (1-440): 0: 715: 99.55		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		428191 TBB5_HUMAN (1-439): 0: 699: 41.23		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1041451 TBA1C_HUMAN (1-451): 0: 728: 98.00		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		933433 TBA4A_HUMAN (1-450): 0: 719: 96.44		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		428192 TBB5_HUMAN (1-439): 0: 699: 41.23		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		1274034 TBA1C_HUMAN (1-451): 0: 728: 98.00		CUL5_HUMAN (59-759): 0: 589: 24.94
+	Hs
		933556 TBA4A_HUMAN (1-450): 0: 719: 96.44		CUL5_HUMAN (59-759): 0: 589: 24.94