HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 451
+	Hs
		522895 TBA4A_HUMAN (1-450): 0: 719: 96.44		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		522894 TBA1B_HUMAN (1-440): 0: 717: 100.00		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		433849 TBA1A_HUMAN (1-440): 0: 715: 99.55		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		427991 TBB5_HUMAN (1-439): 0: 699: 41.23		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		933439 TBA4A_HUMAN (1-450): 0: 719: 96.44		PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00
+	Hs
		411549 TBB5_HUMAN (1-439): 0: 699: 41.23		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		411668 TBB4B_HUMAN (1-437): 0: 697: 40.96		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		428198 TBB5_HUMAN (1-439): 0: 699: 41.23		PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00
+	Hs
		933801 TBB4B_HUMAN (1-437): 0: 697: 40.96		PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00
+	Hs
		428098 TBB5_HUMAN (1-439): 0: 699: 41.23		BLK_HUMAN (7-449): 2e-169: 487: 39.51
+	Hs
		782771 TBA1B_HUMAN (1-440): 0: 717: 100.00		CSK_HUMAN (4-448): 3.18e-160: 461: 35.82