HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24275654
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 2527
+	Hs
		1130508 TBA1C_HUMAN (1-451): 0: 728: 98.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1120842 Q53GA7_HUMAN (1-451): 0: 726: 97.78		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		933472 TBA4A_HUMAN (1-450): 0: 719: 96.44		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130237 TBA1A_HUMAN (1-440): 0: 715: 99.55		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		428247 TBB5_HUMAN (1-439): 0: 699: 41.23		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		933841 TBB4B_HUMAN (1-437): 0: 697: 40.96		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		782771 TBA1B_HUMAN (1-440): 0: 717: 100.00		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74
+	Hs
		428238 TBB5_HUMAN (1-439): 0: 699: 41.23		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		933832 TBB4B_HUMAN (1-437): 0: 697: 40.96		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		201179 TBB5_HUMAN (1-439): 0: 699: 41.23		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83