HitPredict

Interactor 1: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Interactor 2: OPTN (Q96CV9)
Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP)
Gene: OPTN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33545068
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 577
+	Hs
		1175286 TBA1A_HUMAN (1-440): 0: 715: 99.55		NEMO_HUMAN (204-576): 1.98e-39: 150: 25.86
+	Hs
		1348229 TBA8_HUMAN (1-440): 0: 701: 90.68		NEMO_HUMAN (204-576): 1.98e-39: 150: 25.86
+	Hs
		428528 TBB5_HUMAN (1-439): 0: 699: 41.23		NEMO_HUMAN (204-576): 1.98e-39: 150: 25.86
+	Hs
		933807 TBB4B_HUMAN (1-437): 0: 697: 40.96		DCTN1_HUMAN (199-553): 3.22e-27: 119: 17.58
+	Hs
		1309471 TBA1C_HUMAN (1-451): 0: 728: 98.00		CP250_HUMAN (15-545): 9.03e-15: 80.3: 11.07
+	Hs
		551753 TBA1A_HUMAN (1-440): 0: 715: 99.55		DESP_HUMAN (6-522): 2.58e-16: 85.1: 11.60
+	Hs
		933335 TBA1B_HUMAN (1-440): 0: 717: 100.00		CP250_HUMAN (15-545): 9.03e-15: 80.3: 11.07
+	Hs
		1175148 TBA1A_HUMAN (1-440): 0: 715: 99.55		CP250_HUMAN (15-545): 9.03e-15: 80.3: 11.07
+	Hs
		148973 TBA1A_HUMAN (1-440): 0: 715: 99.55		CTRO_HUMAN (7-564): 1.03e-13: 76.6: 11.59
+	Hs
		428403 TBB5_HUMAN (1-439): 0: 699: 41.23		CP250_HUMAN (15-545): 9.03e-15: 80.3: 11.07
+	Hs
		933951 TBB4B_HUMAN (1-437): 0: 697: 40.96		CP250_HUMAN (15-545): 9.03e-15: 80.3: 11.07