Interactor 1: RYR1 (E9PZQ0)
Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)
Gene: RYR1

Interactor 2: FKB1A (P26883)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: Fkbp1a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 18268335, 22939628
Identification Methods anti bait coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FKBP_C~RYDR_ITPR, FKBP_C~SPRY
Common GO terms GO:0005737 - cytoplasm
GO:0006936 - muscle contraction
GO:0016020 - membrane
GO:0016529 - sarcoplasmic reticulum
GO:0019899 - enzyme binding
and 4 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 5035
Mm

1 108
+ Hs
+ Oc
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024