HitPredict

Interactor 1: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Interactor 2: TBCB (Q99426)
Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B)
Gene: TBCB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0015630 - microtubule cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Hs			1 244
+	Hs
		933320 TBA1B_HUMAN (1-439): 0: 715: 97.49		TBCB_HUMAN (1-244): 4.79e-105: 305: 100.00
+	Hs
		1175122 TBA1A_HUMAN (1-439): 0: 712: 97.04		TBCB_HUMAN (1-244): 4.79e-105: 305: 100.00
+	Hs
		1309507 TBA1C_HUMAN (1-448): 0: 726: 96.21		CYLD_HUMAN (16-230): 5.4e-45: 162: 17.89
+	Hs
		933632 TBA4A_HUMAN (1-448): 0: 724: 100.00		CYLD_HUMAN (16-230): 5.4e-45: 162: 17.89
+	Hs
		1175203 TBA1A_HUMAN (1-439): 0: 712: 97.04		CYLD_HUMAN (16-230): 5.4e-45: 162: 17.89
+	Mm
		933729 TBA1A_MOUSE (1-439): 0: 712: 97.04		CYLD_MOUSE (3-230): 1.35e-41: 153: 18.07
+	Hs
		428455 TBB5_HUMAN (1-439): 0: 697: 40.55		CYLD_HUMAN (16-230): 5.4e-45: 162: 17.89
+	Hs
		933989 TBB4B_HUMAN (1-437): 0: 695: 40.28		CYLD_HUMAN (16-230): 5.4e-45: 162: 17.89
+	Hs
		1313680 TBB2B_HUMAN (1-440): 0: 694: 39.77		CYLD_HUMAN (16-230): 5.4e-45: 162: 17.89
+	Hs
		675155 TBA4A_HUMAN (1-448): 0: 724: 100.00		CLIP1_HUMAN (135-240): 3.25e-26: 108: 32.08
+	Hs
		675189 TBA1A_HUMAN (1-439): 0: 712: 97.04		CLIP1_HUMAN (135-240): 3.25e-26: 108: 32.08
+	Hs
		933807 TBB4B_HUMAN (1-437): 0: 695: 40.28		DCTN1_HUMAN (136-233): 3.43e-30: 120: 39.80
+	Hs
		1175224 TBA1A_HUMAN (1-439): 0: 712: 97.04		CLIP2_HUMAN (122-231): 1.31e-23: 101: 34.55
+	Hs
		933892 TBB4B_HUMAN (1-437): 0: 695: 40.28		CLIP4_HUMAN (71-230): 1.75e-27: 112: 25.00
+	Hs
		428038 TBB5_HUMAN (1-439): 0: 697: 40.55		CLIP1_HUMAN (135-240): 3.25e-26: 108: 32.08
+	Hs
		428228 TBB5_HUMAN (1-439): 0: 697: 40.55		TBCE_HUMAN (152-242): 1.27e-25: 106: 29.91
+	Hs
		675156 TBB4B_HUMAN (1-437): 0: 695: 40.28		CLIP1_HUMAN (135-240): 3.25e-26: 108: 32.08
+	Hs
		933827 TBB4B_HUMAN (1-437): 0: 695: 40.28		TBCE_HUMAN (152-242): 1.27e-25: 106: 29.91
+	Hs
		675240 TBA8_HUMAN (1-440): 0: 691: 90.23		CLIP1_HUMAN (135-240): 3.25e-26: 108: 32.08
+	Hs
		934011 TBB4B_HUMAN (1-437): 0: 695: 40.28		CLIP2_HUMAN (122-231): 1.31e-23: 101: 34.55