HitPredict

Interactor 1: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Interactor 2: KLK15 (Q9H2R5)
Kallikrein-15 (EC 3.4.21.-) (ACO protease)
Gene: KLK15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Hs			1 256
+	Hs
		1309491 TBA1C_HUMAN (1-448): 0: 726: 96.21		KLK15_HUMAN (1-256): 3.74e-114: 329: 100.00
+	Hs
		714751 TBA1B_HUMAN (1-439): 0: 715: 97.49		TRY3_HUMAN (8-256): 1.1e-114: 332: 41.37
+	Hs
		1175174 TBA1A_HUMAN (1-439): 0: 712: 97.04		KLK15_HUMAN (1-256): 3.74e-114: 329: 100.00
+	Hs
		933554 TBA4A_HUMAN (1-448): 0: 724: 100.00		KLK6_HUMAN (1-255): 1.16e-108: 315: 43.14
+	Hs
		1309527 TBA1C_HUMAN (1-448): 0: 726: 96.21		KLK11_HUMAN (19-256): 3.18e-107: 312: 50.41
+	Hs
		933653 TBA4A_HUMAN (1-448): 0: 724: 100.00		KLK11_HUMAN (19-256): 3.18e-107: 312: 50.41
+	Hs
		1175223 TBA1A_HUMAN (1-439): 0: 712: 97.04		KLK11_HUMAN (19-256): 3.18e-107: 312: 50.41
+	Hs
		1309540 TBA1C_HUMAN (1-448): 0: 726: 96.21		KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46
+	Hs
		933677 TBA4A_HUMAN (1-448): 0: 724: 100.00		KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46
+	Hs
		933221 TBA1B_HUMAN (1-439): 0: 715: 97.49		PRSS8_HUMAN (10-253): 4.37e-98: 292: 33.46
+	Hs
		1175268 TBA1A_HUMAN (1-439): 0: 712: 97.04		KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46
+	Hs
		428515 TBB5_HUMAN (1-439): 0: 697: 40.55		KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46
+	Hs
		934035 TBB4B_HUMAN (1-437): 0: 695: 40.28		KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46
+	Hs
		1348218 TBA8_HUMAN (1-440): 0: 691: 90.23		KLK12_HUMAN (1-256): 1.5e-96: 284: 45.56
+	Hs
		595562 TBA1C_HUMAN (1-448): 0: 726: 96.21		GRAH_HUMAN (14-255): 1.82e-48: 162: 37.10
+	Hs
		595527 TBA4A_HUMAN (1-448): 0: 724: 100.00		GRAH_HUMAN (14-255): 1.82e-48: 162: 37.10
+	Hs
		595544 TBA1A_HUMAN (1-439): 0: 712: 97.04		GRAH_HUMAN (14-255): 1.82e-48: 162: 37.10
+	Mm
		371482 TBA1B_MOUSE (1-439): 0: 715: 97.49		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40
+	Hs
		428017 TBB5_HUMAN (1-439): 0: 697: 40.55		GRAH_HUMAN (14-255): 1.82e-48: 162: 37.10
+	Mm
		371765 TBB4B_MOUSE (1-437): 0: 695: 40.28		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40