HitPredict

Interactor 1: TBA4A (P68368)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 4) (Alpha-tubulin isotype M-alpha-4) (Tubulin alpha-4 chain)
Gene: Tuba4a

Interactor 2: SHC1 (P98083)
SHC-transforming protein 1 (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	20697350
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Mm			1 579
+	Hs
		666163 TBA1C_HUMAN (1-448): 0: 726: 96.21		SHC1_HUMAN (1-579): 5.04e-179: 520: 94.17
+	Hs
		666063 TBA1B_HUMAN (1-439): 0: 715: 97.49		SHC1_HUMAN (1-579): 5.04e-179: 520: 94.17
+	Hs
		666131 TBA1A_HUMAN (1-439): 0: 712: 97.04		SHC1_HUMAN (1-579): 5.04e-179: 520: 94.17
+	Hs
		428036 TBB5_HUMAN (1-439): 0: 697: 40.55		SHC1_HUMAN (1-579): 5.04e-179: 520: 94.17
+	Hs
		522895 TBA4A_HUMAN (1-448): 0: 724: 100.00		SRC_HUMAN (334-570): 7.45e-44: 166: 16.87
+	Mm
		57446 TBA1A_MOUSE (1-439): 0: 712: 97.04		A2AM67_MOUSE (191-571): 3.36e-48: 175: 15.19
+	Hs
		933524 TBA4A_HUMAN (1-448): 0: 724: 100.00		SH2D3_HUMAN (333-578): 1.56e-40: 159: 22.75
+	Hs
		522894 TBA1B_HUMAN (1-439): 0: 715: 97.49		SRC_HUMAN (334-570): 7.45e-44: 166: 16.87
+	Mm
		958399 TBB5_MOUSE (1-439): 0: 697: 40.55		ANS1B_MOUSE (39-364): 1.35e-48: 184: 17.96
+	Hs
		557723 TBA1A_HUMAN (1-439): 0: 712: 97.04		NCK1_HUMAN (360-571): 3.06e-42: 157: 19.37
+	Hs
		427991 TBB5_HUMAN (1-439): 0: 697: 40.55		SRC_HUMAN (334-570): 7.45e-44: 166: 16.87
+	Hs
		428098 TBB5_HUMAN (1-439): 0: 697: 40.55		BLK_HUMAN (362-577): 2.17e-40: 155: 18.14
+	Hs
		129329 TBA1C_HUMAN (1-448): 0: 726: 96.21		P85B_HUMAN (479-576): 2.03e-18: 91.2: 23.53
+	Hs
		655312 TBA1B_HUMAN (1-439): 0: 715: 97.49		P85A_HUMAN (479-575): 6.35e-19: 92.7: 24.75
+	Hs
		924827 TBA1C_HUMAN (1-448): 0: 726: 96.21		GRB2_HUMAN (478-574): 1.33e-15: 77.9: 30.48
+	Hs
		924459 TBA4A_HUMAN (1-448): 0: 724: 100.00		GRB2_HUMAN (478-574): 1.33e-15: 77.9: 30.48
+	Hs
		1175137 TBA1A_HUMAN (1-439): 0: 712: 97.04		SH23A_HUMAN (471-577): 4.02e-17: 86.8: 33.06
+	Hs
		924458 TBA1B_HUMAN (1-439): 0: 715: 97.49		GRB2_HUMAN (478-574): 1.33e-15: 77.9: 30.48
+	Hs
		129166 TBB5_HUMAN (1-439): 0: 697: 40.55		P85B_HUMAN (479-576): 2.03e-18: 91.2: 23.53
+	Hs
		428131 TBB5_HUMAN (1-439): 0: 697: 40.55		GRB2_HUMAN (478-574): 1.33e-15: 77.9: 30.48