HitPredict

Interactor 1: TBA1A (P68369)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Alpha-tubulin isotype M-alpha-1) (Tubulin alpha-1 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: Tuba1a

Interactor 2: HDAC6 (Q9Z2V5)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Histone deacetylase mHDA2) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	12486003, 19893491
Identification Methods	enzymatic study, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 451 Mm			1 1149
+	Hs
		1309525 TBA1C_HUMAN (1-451): 0: 726: 98.00		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		933651 TBA4A_HUMAN (1-450): 0: 717: 96.00		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		933376 TBA1B_HUMAN (1-440): 0: 715: 99.55		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		1175219 TBA1A_HUMAN (1-440): 0: 713: 100.00		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		1348213 TBA8_HUMAN (1-440): 0: 701: 90.68		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		428477 TBB5_HUMAN (1-439): 0: 695: 40.77		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		934008 TBB4B_HUMAN (1-437): 0: 693: 40.50		HDAC6_HUMAN (1-1149): 0: 1271: 74.57
+	Hs
		880679 TBA4A_HUMAN (1-450): 0: 717: 96.00		HDAC4_HUMAN (404-863): 1.29e-142: 459: 36.57
+	Hs
		428188 TBB5_HUMAN (1-439): 0: 695: 40.77		HDAC1_HUMAN (470-870): 2.47e-156: 476: 20.75
+	Hs
		933791 TBB4B_HUMAN (1-437): 0: 693: 40.50		HDAC1_HUMAN (470-870): 2.47e-156: 476: 20.75
+	Hs
		1175252 TBA1A_HUMAN (1-440): 0: 713: 100.00		HDAC5_HUMAN (439-878): 1.24e-139: 453: 35.89
+	Hs
		428112 TBB5_HUMAN (1-439): 0: 695: 40.77		HDAC4_HUMAN (404-863): 1.29e-142: 459: 36.57
+	Hs
		428502 TBB5_HUMAN (1-439): 0: 695: 40.77		HDAC5_HUMAN (439-878): 1.24e-139: 453: 35.89
+	Hs
		934028 TBB4B_HUMAN (1-437): 0: 693: 40.50		HDAC5_HUMAN (439-878): 1.24e-139: 453: 35.89