HitPredict

Interactor 1: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Interactor 2: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 638
+	Hs
		381190 TBB4A_HUMAN (1-427): 0: 706: 98.60		DC1I2_HUMAN (1-638): 3.3e-143: 432: 100.00
+	Hs
		148067 TBB3_HUMAN (1-443): 0: 714: 93.23		DC1I1_HUMAN (1-638): 2.67e-129: 396: 75.04
+	Hs
		1114123 TBB8_HUMAN (1-427): 0: 704: 91.10		WDR5B_HUMAN (367-626): 3.82e-61: 208: 16.15
+	Hs
		1114207 TBB8_HUMAN (1-427): 0: 704: 91.10		TBL1Y_HUMAN (364-623): 5.21e-45: 169: 14.55
+	Hs
		903201 TBB3_HUMAN (1-443): 0: 714: 93.23		WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11
+	Hs
		428123 TBB5_HUMAN (1-429): 0: 711: 98.37		WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11
+	Hs
		903115 TBB4B_HUMAN (1-427): 0: 711: 100.00		WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11
+	Hs
		381159 TBB4A_HUMAN (1-427): 0: 706: 98.60		WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11
+	Hs
		903481 TBB6_HUMAN (1-432): 0: 706: 92.36		WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11
+	Hs
		792969 TBB4B_HUMAN (1-427): 0: 711: 100.00		LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88
+	Ce
		953946 Q18817_CAEEL (1-444): 0: 715: 91.89		LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50
+	Ce
		185041 O17921_CAEEL (1-443): 0: 710: 90.75		LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50
+	Ce
		853143 TBB2_CAEEL (1-444): 0: 708: 90.32		LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50
+	Ce
		519704 TBB1_CAEEL (1-441): 0: 703: 92.52		LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50