HitPredict

Interactor 1: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Interactor 2: EMAL3 (Q32P44)
Echinoderm microtubule-associated protein-like 3 (EMAP-3)
Gene: EML3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0015630 - microtubule cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 896
+	Hs
		1104144 TBB2B_HUMAN (1-430): 0: 710: 98.14		EMAL3_HUMAN (1-896): 0: 558: 100.00
+	Hs
		903201 TBB3_HUMAN (1-443): 0: 714: 93.23		WDR5_HUMAN (60-390): 5.42e-34: 135: 11.34
+	Hs
		428123 TBB5_HUMAN (1-429): 0: 711: 98.37		WDR5_HUMAN (60-390): 5.42e-34: 135: 11.34
+	Hs
		903115 TBB4B_HUMAN (1-427): 0: 711: 100.00		WDR5_HUMAN (60-390): 5.42e-34: 135: 11.34
+	Hs
		325564 TBB3_HUMAN (1-443): 0: 714: 93.23		EMAL2_HUMAN (587-896): 6.05e-26: 116: 13.62
+	Hs
		325560 TBB4B_HUMAN (1-427): 0: 711: 100.00		EMAL2_HUMAN (587-896): 6.05e-26: 116: 13.62
+	Hs
		1037266 TBB3_HUMAN (1-443): 0: 714: 93.23		EMAL6_HUMAN (582-896): 2.86e-24: 112: 7.18
+	Hs
		325572 TBB2B_HUMAN (1-430): 0: 710: 98.14		EMAL2_HUMAN (587-896): 6.05e-26: 116: 13.62
+	Hs
		325565 TBB2A_HUMAN (1-430): 0: 707: 97.67		EMAL2_HUMAN (587-896): 6.05e-26: 116: 13.62
+	Hs
		1168501 TBB2B_HUMAN (1-430): 0: 710: 98.14		EMAL6_HUMAN (582-896): 2.86e-24: 112: 7.18
+	Hs
		1037405 TBB3_HUMAN (1-443): 0: 714: 93.23		EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51
+	Hs
		428448 TBB5_HUMAN (1-429): 0: 711: 98.37		EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51
+	Hs
		933982 TBB4B_HUMAN (1-427): 0: 711: 100.00		EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51
+	Hs
		1313678 TBB2B_HUMAN (1-430): 0: 710: 98.14		EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51
+	Hs
		428163 TBB5_HUMAN (1-429): 0: 711: 98.37		TBL3_HUMAN (92-298): 1.15e-15: 83.9: 8.33
+	Hs
		267759 TBB3_HUMAN (1-443): 0: 714: 93.23		TAF5L_HUMAN (669-889): 6.88e-14: 77.6: 20.48
+	Hs
		127920 TBB3_HUMAN (1-443): 0: 714: 93.23		EMAL1_HUMAN (760-894): 5.57e-09: 61.9: 8.11
+	Hs
		127909 TBB5_HUMAN (1-429): 0: 711: 98.37		EMAL1_HUMAN (760-894): 5.57e-09: 61.9: 8.11
+	Hs
		127928 TBB2B_HUMAN (1-430): 0: 710: 98.14		EMAL1_HUMAN (760-894): 5.57e-09: 61.9: 8.11
+	Hs
		127921 TBB2A_HUMAN (1-430): 0: 707: 97.67		EMAL1_HUMAN (760-894): 5.57e-09: 61.9: 8.11