HitPredict

Interactor 1: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	26643866, 30009671, 35676659, 23703321
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 1215
+	Hs
		1037423 TBB3_HUMAN (1-443): 0: 714: 93.23		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		428477 TBB5_HUMAN (1-429): 0: 711: 98.37		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1313689 TBB2B_HUMAN (1-430): 0: 710: 98.14		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1046606 TBB2A_HUMAN (1-430): 0: 707: 97.67		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1312828 TBB6_HUMAN (1-432): 0: 706: 92.36		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		381319 TBB4A_HUMAN (1-427): 0: 706: 98.60		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1037214 TBB3_HUMAN (1-443): 0: 714: 93.23		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		428188 TBB5_HUMAN (1-429): 0: 711: 98.37		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		933791 TBB4B_HUMAN (1-427): 0: 711: 100.00		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		1038678 TBB6_HUMAN (1-432): 0: 706: 92.36		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		880716 TBB3_HUMAN (1-443): 0: 714: 93.23		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		428112 TBB5_HUMAN (1-429): 0: 711: 98.37		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		880721 TBB2A_HUMAN (1-430): 0: 707: 97.67		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		428502 TBB5_HUMAN (1-429): 0: 711: 98.37		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		934028 TBB4B_HUMAN (1-427): 0: 711: 100.00		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		1114178 TBB8_HUMAN (1-427): 0: 704: 91.10		HDA10_HUMAN (85-449): 8.19e-152: 473: 53.53