HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	33545068, 27846364, 22017874
Identification Methods	proximity labelling technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0016605 - PML body
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 440
+	Hs
		625413 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		586729 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		835732 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		319764 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		835756 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78