Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 16335536, 35271311
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~Pkinase, CDC37_N~Pkinase
Common GO terms GO:0005829 - cytosol
GO:0050821 - protein stabilization
GO:0051879 - Hsp90 protein binding
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 391
Hs

1 378
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024