HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: PCGF3 (Q3KNV8)
Polycomb group RING finger protein 3 (RING finger protein 3A)
Gene: PCGF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	27705803, 35271311, 32707033, 36736316, 24981860, 33961781, 22325352
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 242
+	Hs
		1108520 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		PCGF3_HUMAN (1-242): 8.16e-66: 205: 100.00
+	Hs
		717679 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76
+	Hs
		718389 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03
+	Hs
		625171 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76
+	Hs
		934433 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		PCGF1_HUMAN (3-238): 1.66e-45: 154: 38.33
+	Hs
		934449 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		PCGF6_HUMAN (3-235): 4.63e-43: 150: 33.62
+	Hs
		586591 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		BMI1_HUMAN (3-238): 2.96e-60: 194: 33.76
+	Dm
		437099 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		Q9VV77_DROME (2-241): 5.3e-50: 164: 54.55
+	Hs
		586592 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		PCGF2_HUMAN (3-238): 5.76e-59: 191: 34.03
+	Hs
		934279 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		PCGF5_HUMAN (4-241): 3.95e-40: 140: 38.06
+	Hs
		1197573 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		PCGF5_HUMAN (4-241): 3.95e-40: 140: 38.06
+	Hs
		934417 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		RING2_HUMAN (2-237): 3.42e-36: 132: 18.00
+	Hs
		934122 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		RING1_HUMAN (3-172): 3.16e-35: 131: 20.81
+	Mm
		1141316 CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Mm
		1142258 Q61177_MOUSE (1-391): 1.81e-133: 389: 98.47		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Hs
		1243548 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		RING2_HUMAN (2-237): 3.42e-36: 132: 18.00
+	Hs
		584875 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		RO52_HUMAN (2-241): 3.02e-47: 164: 15.56
+	Hs
		987994 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		RING1_HUMAN (3-172): 3.16e-35: 131: 20.81
+	Mm
		222427 CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08		RING2_MOUSE (2-237): 2.47e-36: 132: 18.00
+	Hs
		586701 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		RING1_HUMAN (3-172): 3.16e-35: 131: 20.81