Interactor 1: RYR2 (E9Q401)
Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Interactor 2: RYR2 (E9Q401)
Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.744

The method score is based on:

Property Details
Experiments 20427316, 12324472
Identification Methods fluorescence recovery after photobleaching, electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~EF-hand_7, EF-hand_7~Ion_trans, Ins145_P3_rec~Ins145_P3_rec, Ins145_P3_rec~MIR, Ins145_P3_rec~RIH_assoc, Ins145_P3_rec~RYDR_ITPR, Ion_trans~Ion_trans, Ion_trans~RR_TM4-6, MIR~MIR, MIR~RYDR_ITPR, RR_TM4-6~RR_TM4-6, RYDR_ITPR~RYDR_ITPR, RYDR_ITPR~SPRY, RyR~RyR, RyR~SPRY, SPRY~SPRY
Common GO terms GO:0001666 - response to hypoxia
GO:0002027 - regulation of heart rate
GO:0003143 - embryonic heart tube morphogenesis
GO:0003220 - left ventricular cardiac muscle tissue morphogenesis
GO:0003300 - cardiac muscle hypertrophy
and 60 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 4966
Mm

1 4966
+ Hs
+ Hs
+ Mm
+ Hs
+ Oc
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024