HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.849

Property	Details
Experiments	29568061, 15100215, 19358706
Identification Methods	proximity labelling technology, unspecified method, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 290
+	Hs
		963827 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		SET_HUMAN (1-236): 6.45e-89: 268: 100.00
+	Hs
		952277 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		SET_HUMAN (1-236): 6.45e-89: 268: 100.00
+	Hs
		934935 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69
+	Hs
		963844 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		SET_HUMAN (1-236): 6.45e-89: 268: 100.00
+	Hs
		952444 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69
+	Hs
		1086346 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		TSYL4_HUMAN (31-235): 7.34e-85: 261: 36.59
+	Hs
		876755 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		876827 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		1086291 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81
+	Hs
		1174639 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81
+	At
		886474 H33_ARATH (1-136): 7.67e-62: 187: 96.32		NAP1A_ARATH (18-239): 3.58e-72: 228: 22.55
+	At
		886475 H33_ARATH (1-136): 7.67e-62: 187: 96.32		NAP1B_ARATH (18-238): 2.68e-72: 228: 22.71
+	At
		886671 H31_ARATH (1-136): 1.67e-60: 184: 97.06		NAP1A_ARATH (18-239): 3.58e-72: 228: 22.55
+	At
		886672 H31_ARATH (1-136): 1.67e-60: 184: 97.06		NAP1B_ARATH (18-238): 2.68e-72: 228: 22.71
+	At
		886466 H33_ARATH (1-136): 7.67e-62: 187: 96.32		NAP1C_ARATH (18-239): 6.06e-71: 224: 22.99
+	At
		886665 H31_ARATH (1-136): 1.67e-60: 184: 97.06		NAP1C_ARATH (18-239): 6.06e-71: 224: 22.99
+	Dm
		356123 H3_DROME (1-136): 6.5e-61: 185: 99.27		Q9W1G7_DROME (18-238): 1.82e-67: 216: 20.54
+	Sc
		627669 H3_YEAST (1-136): 1.16e-55: 172: 88.97		NAP1_YEAST (6-286): 9.91e-70: 223: 20.45
+	Sc
		627600 CENPA_YEAST (18-134): 2.12e-41: 138: 55.83		NAP1_YEAST (6-286): 9.91e-70: 223: 20.45