Interactor 1: RYR2 (E9Q401)
Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Interactor 2: KCC2D (Q6PHZ2)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: Camk2d

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 20479242, 24952909
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Pkinase, Pkinase~RyR
Common GO terms GO:0001666 - response to hypoxia
GO:0005516 - calmodulin binding
GO:0006816 - calcium ion transport
GO:0032991 - protein-containing complex
GO:0033017 - sarcoplasmic reticulum membrane
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 4966
Mm

1 499
+ Hs
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Last updated: 15 Jul 2024