HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.953

Property	Details
Experiments	25533843, 29020631, 29568061, 34079125, 36089195, 16728976, 11850410
Identification Methods	affinity chromatography technology, pull down, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 2000
+	Hs
		935016 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD5_HUMAN (43-1961): 0: 1610: 66.45
+	Hs
		1086233 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CHD5_HUMAN (43-1961): 0: 1610: 66.45
+	Mm
		56901 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		CHD5_MOUSE (43-1933): 0: 1561: 66.97
+	Hs
		934770 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		1059646 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		935014 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD6_HUMAN (218-1804): 0: 861: 24.77
+	Hs
		1086232 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CHD6_HUMAN (218-1804): 0: 861: 24.77
+	Hs
		935262 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		935324 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Mm
		935460 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		SMCA5_MOUSE (612-1612): 0: 781: 28.28
+	Mm
		952763 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		SMCA5_MOUSE (612-1612): 0: 781: 28.28
+	Hs
		229359 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Hs
		229363 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Hs
		658647 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SMCA1_HUMAN (622-1597): 0: 776: 28.08
+	Hs
		151396 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CHD1_HUMAN (507-1729): 0: 746: 29.81
+	Hs
		151419 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CHD1_HUMAN (507-1729): 0: 746: 29.81
+	Hs
		151399 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		CHD1_HUMAN (507-1729): 0: 746: 29.81
+	Mm
		770296 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		CHD1_MOUSE (505-1729): 0: 742: 29.41
+	Hs
		151487 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		CHD2_HUMAN (540-1666): 0: 733: 31.02
+	Hs
		846743 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SMCA2_HUMAN (73-1644): 0: 718: 20.07