HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

Property	Details
Experiments	26527279, 24981860, 34133717, 36089195, 15136563, 20011120, 24576085, 33097091, 16415788, 20871592
Identification Methods	biochemical, affinity chromatography technology, proximity labelling technology, pull down, x-ray crystallography, unspecified method, tandem affinity purification, protein array
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 183
+	Hs
		1027017 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800341 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		800397 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		934657 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Mm
		935445 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		949795 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		935237 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV92_HUMAN (6-156): 4.05e-43: 149: 25.15
+	Hs
		203659 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		935387 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16
+	Hs
		327837 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX7_HUMAN (21-181): 5.6e-29: 109: 22.78
+	Hs
		123231 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		327844 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX7_HUMAN (21-181): 5.6e-29: 109: 22.78
+	Hs
		123254 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		316000 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		316040 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		935259 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX8_HUMAN (21-116): 2.34e-26: 104: 32.00
+	Hs
		934768 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CBX2_HUMAN (20-117): 5.97e-25: 102: 27.00
+	Hs
		934987 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		CDYL2_HUMAN (28-125): 3.12e-25: 102: 28.43
+	Hs
		1059154 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CBX2_HUMAN (20-117): 5.97e-25: 102: 27.00
+	Hs
		1086221 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		CDYL2_HUMAN (28-125): 3.12e-25: 102: 28.43