HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	29568061, 34079125, 36089195, 34349018, 35271311
Identification Methods	proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 2115
+	Hs
		952344 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061148 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		724769 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		725137 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		1068543 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		725188 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		518850 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04
+	Hs
		935392 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		MYH15_HUMAN (973-1671): 5.68e-09: 63.9: 20.39