HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: MED1 (Q15648)
Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2) (Vitamin D receptor-interacting protein complex component DRIP205) (p53 regulatory protein RB18A)
Gene: MED1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1581
+	Hs
		952359 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		MED1_HUMAN (1-1581): 0: 1281: 100.00
+	Hs
		952297 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		ARHG5_HUMAN (873-1555): 6.74e-24: 112: 12.75
+	Mm
		101827 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		F8WI37_MOUSE (1008-1567): 1.2e-17: 92.1: 10.12
+	Hs
		934763 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		MDC1_HUMAN (751-1577): 1.19e-16: 88.6: 8.40
+	Hs
		952338 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		MDC1_HUMAN (751-1577): 1.19e-16: 88.6: 8.40
+	Hs
		934881 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Hs
		952407 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Hs
		1174677 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		RERE_HUMAN (997-1464): 1.82e-14: 81.5: 16.56
+	Hs
		935004 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KMT2C_HUMAN (1092-1565): 3.68e-11: 70.9: 12.71
+	Hs
		1086228 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KMT2C_HUMAN (1092-1565): 3.68e-11: 70.9: 12.71
+	Hs
		952479 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KMT2C_HUMAN (1092-1565): 3.68e-11: 70.9: 12.71
+	Hs
		1174600 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		KMT2C_HUMAN (1092-1565): 3.68e-11: 70.9: 12.71
+	Hs
		934908 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		SRCAP_HUMAN (539-1053): 4.95e-09: 63.6: 11.43
+	Hs
		934668 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		ANK2_HUMAN (662-1563): 9.43e-09: 62.7: 11.52
+	Hs
		952426 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		SRCAP_HUMAN (539-1053): 4.95e-09: 63.6: 11.43
+	Hs
		965127 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		ANK2_HUMAN (662-1563): 9.43e-09: 62.7: 11.52
+	Hs
		828271 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		NIPBL_HUMAN (984-1563): 7.42e-16: 86.1: 16.01
+	Hs
		828275 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		ANR11_HUMAN (534-1294): 1.03e-12: 75.9: 7.58
+	Sc
		730797 CENPA_YEAST (18-134): 2.12e-41: 138: 55.83		SEC31_YEAST (999-1482): 4.61e-14: 79.9: 16.06
+	Sc
		730824 CENPA_YEAST (18-134): 2.12e-41: 138: 55.83		NU159_YEAST (1097-1567): 6.5e-12: 73: 20.16