Interactor 1: RYR2 (E9Q401)
Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2
Interactor 2: FKB1B (Q9Z2I2)
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase)
Gene: Fkbp1b
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.60 | 1.00 | 0.776 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | EF-hand_7~FKBP_C, FKBP_C~RYDR_ITPR, FKBP_C~SPRY |
Common GO terms | GO:0002027 - regulation of heart rate GO:0010881 - regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0016529 - sarcoplasmic reticulum GO:0030018 - Z disc GO:0033017 - sarcoplasmic reticulum membrane and 3 others more... |
Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024