HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: KDM1B (Q8NB78)
Lysine-specific histone demethylase 2 (EC 1.14.99.66) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 1B)
Gene: KDM1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	23266887, 25281560, 36089195
Identification Methods	x-ray crystallography, proximity labelling technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	Amino_oxidase~Histone
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 822
+	Hs
		1086222 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KDM1B_HUMAN (1-822): 0: 1136: 100.00
+	Hs
		952473 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KDM1B_HUMAN (1-822): 0: 1136: 100.00
+	Hs
		232094 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Hs
		232190 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Hs
		232104 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Hs
		232270 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Hs
		232248 H3C_HUMAN (1-136): 5.49e-58: 177: 93.38		KDM1A_HUMAN (278-821): 1.75e-142: 443: 25.41
+	Dm
		356119 H3_DROME (1-136): 6.5e-61: 185: 99.27		LSDA_DROME (233-822): 6.39e-123: 393: 22.60