HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: KDM2B (Q8NHM5)
Lysine-specific demethylase 2B (EC 1.14.11.27) (CXXC-type zinc finger protein 2) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (Protein JEMMA) (Protein-containing CXXC domain 2) ([Histone-H3]-lysine-36 demethylase 1B)
Gene: KDM2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	36089195, 17994099, 31531877, 22825849
Identification Methods	proximity labelling technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1336
+	Hs
		952482 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Hs
		1174601 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Hs
		828308 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		KDM2B_HUMAN (1-1336): 0: 1220: 100.00
+	Hs
		935373 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		1086352 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		952701 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Hs
		1157239 H3C_HUMAN (1-136): 5.49e-58: 177: 93.38		PHF8_HUMAN (22-1018): 0: 637: 20.63
+	Dm
		356110 H3_DROME (1-136): 6.5e-61: 185: 99.27		JHD1_DROME (46-1233): 0: 600: 24.77
+	Hs
		256400 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256412 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256401 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Hs
		256416 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Ce
		445734 H3_CAEEL (1-136): 1.21e-60: 184: 97.79		KDM7_CAEEL (22-553): 8.84e-164: 515: 24.73
+	Hs
		256390 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		PHF2_HUMAN (22-1045): 4.96e-172: 543: 18.72
+	Sc
		767176 H3_YEAST (1-136): 1.16e-55: 172: 88.97		JHD1_YEAST (53-390): 3.17e-133: 420: 34.30
+	Hs
		935393 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		1086360 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		952712 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		1174697 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		KDM2A_HUMAN (845-1336): 9.67e-66: 246: 41.46
+	Hs
		1174674 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		CXXC1_HUMAN (607-651): 5.77e-09: 62.4: 58.70