HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: SETD7 (Q8WTS6)
Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9)
Gene: SETD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.937

Property	Details
Experiments	16415881, 11779497, 15525938, 22403242, 12540855
Identification Methods	enzymatic study, x-ray crystallography, methyltransferase assay, nuclear magnetic resonance
Interaction Type	direct interaction, association, methylation reaction

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 366
+	Hs
		1086237 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		SETD7_HUMAN (1-366): 8.9e-159: 451: 100.00
+	Hs
		952491 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		SETD7_HUMAN (1-366): 8.9e-159: 451: 100.00
+	Hs
		1174608 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		JPH3_HUMAN (2-70): 9.15e-10: 62.4: 28.99
+	Hs
		1086297 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		JPH2_HUMAN (80-136): 7.35e-09: 59.3: 24.56