HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32451438
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 245
+	Hs
		584928 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RO52_HUMAN (6-157): 6.92e-32: 123: 17.11
+	Hs
		935154 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		1086286 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		935190 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		TRAF4_HUMAN (8-207): 1.85e-27: 111: 13.14
+	Hs
		551436 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RAG1_HUMAN (8-147): 1.08e-26: 110: 19.31
+	Hs
		952576 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		952625 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RNF41_HUMAN (1-158): 7.35e-29: 112: 20.96
+	Hs
		551443 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RAG1_HUMAN (8-147): 1.08e-26: 110: 19.31
+	Hs
		1157225 H3C_HUMAN (1-136): 5.49e-58: 177: 93.38		TRIM4_HUMAN (10-142): 6.25e-29: 115: 13.33
+	Hs
		952608 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		TRI31_HUMAN (6-156): 1.18e-25: 105: 17.65
+	Hs
		934691 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Hs
		987976 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Hs
		952292 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Hs
		828356 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		828206 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40