HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: AURKC (Q9UQB9)
Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)
Gene: AURKC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15316025
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 309
+	Mm
		250432 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		AURKB_MOUSE (2-305): 5.82e-142: 405: 73.03
+	Hs
		682163 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		AKT2_HUMAN (5-309): 1.4e-135: 394: 30.09
+	Hs
		160506 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		AURKA_HUMAN (1-299): 1.69e-135: 391: 64.90
+	Hs
		160599 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		AURKA_HUMAN (1-299): 1.69e-135: 391: 64.90
+	Hs
		935110 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		1086273 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		952545 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		1174628 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Mm
		952738 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		AURKA_MOUSE (2-308): 3.54e-133: 385: 63.90
+	Hs
		610712 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		610715 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		610742 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		1157219 H3C_HUMAN (1-136): 5.49e-58: 177: 93.38		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Dm
		356080 H3_DROME (1-136): 6.5e-61: 185: 99.27		Q27393_DROME (2-298): 1.17e-128: 374: 55.52
+	At
		886668 H31_ARATH (1-136): 1.67e-60: 184: 97.06		AUR1_ARATH (36-297): 3.25e-125: 361: 62.50
+	Hs
		828344 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		828423 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Dm
		356113 H3_DROME (1-136): 6.5e-61: 185: 99.27		AURKB_DROME (42-295): 1.21e-95: 287: 51.56
+	Sc
		758807 H3_YEAST (1-136): 1.16e-55: 172: 88.97		IPL1_YEAST (33-293): 2.31e-82: 254: 48.86
+	Sc
		730798 CENPA_YEAST (18-134): 2.12e-41: 138: 55.83		IPL1_YEAST (33-293): 2.31e-82: 254: 48.86