HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: ASF1A (Q9Y294)
Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)
Gene: ASF1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.97	1.00	0.987

Property	Details
Experiments	24981860, 33961781, 20393127, 22407294, 15664198, 25281560, 28514442, 18971269, 23828041, 29568061, 34079125, 34786730, 36089195, 14718166, 20504901, 19410544, 26167883, unassigned1655, 19498464
Identification Methods	affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	ASF1_hist_chap~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 204
+	Mm
		935461 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		ASF1A_MOUSE (1-204): 1.45e-128: 361: 99.51
+	Hs
		1086358 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Hs
		952711 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Mm
		952765 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		ASF1A_MOUSE (1-204): 1.45e-128: 361: 99.51
+	Gg
		952779 H33_CHICK (1-136): 2.73e-61: 186: 96.32		ASF1_CHICK (1-204): 2.31e-128: 361: 100.00
+	Hs
		1174696 H32_HUMAN (1-136): 6.5e-61: 185: 99.27		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Mm
		952267 H32_MOUSE (1-136): 6.5e-61: 185: 99.27		ASF1A_MOUSE (1-204): 1.45e-128: 361: 99.51
+	Gg
		952273 H32_CHICK (1-136): 6.5e-61: 185: 99.27		ASF1_CHICK (1-204): 2.31e-128: 361: 100.00
+	Hs
		935298 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Hs
		1086330 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Hs
		952660 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Mm
		935463 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		ASF1B_MOUSE (1-204): 7.93e-117: 332: 72.06
+	Mm
		952769 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		ASF1B_MOUSE (1-204): 7.93e-117: 332: 72.06
+	Mm
		952269 H32_MOUSE (1-136): 6.5e-61: 185: 99.27		ASF1B_MOUSE (1-204): 7.93e-117: 332: 72.06
+	Hs
		828399 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Dm
		356097 H3_DROME (1-136): 6.5e-61: 185: 99.27		ASF1_DROME (1-203): 1.05e-97: 284: 56.88
+	Sp
		251626 H31_SCHPO (1-136): 3.54e-59: 181: 91.91		ASF1_SCHPO (1-169): 1.83e-84: 252: 51.43
+	Sc
		689932 H3_YEAST (1-136): 1.16e-55: 172: 88.97		ASF1_YEAST (1-168): 7.8e-88: 261: 54.76